Supply Chain Senior Manager

Senior Manager, Cell and Gene Therapy Commercial Supply Chain – Commercial Manufacturing & Supply Chain, Vertex Pharmaceuticals (Boston) 

The Senior Manager of Cell and Gene Therapy Commercial Supply Chain will drive slot management operations to support Vertex’s autologous cell and gene therapy program.  The slot management model includes dynamic, short range, and situational planning and operations to allow visibility and patient scheduling. The Senior Manager will be responsible for establishing, maintaining, revising, and executing slot management rules and principles to ensure patients are appropriately scheduled within manufacturing capacity and regulatory requirements. This includes chairing CDMO and cross-functional meetings and driving content of key presentations to cross-functional leaders.  Through cross-functional alignment, the Senior Manager will drive the data used in the creation, maintenance, and usage of a Key Performance Indicators (KPIs) Dashboard. In this role, the Senior Manager will be responsible for creating business processes and opportunities to ensure capacity utilization across the Supply Chain network. This includes representation as key Supply Chain lead for cross-functional workstreams and initiatives. The Senior Manager will work closely with key stakeholders including the Finance, Regulatory, Commercial, Logistics, Manufacturing, and Vertex’s Cell and Gene Therapy Site.   

Key Responsibilities: 

• Lead initiatives to deliver innovative and impactful business results by leveraging knowledge of CGT Supply Chain processes. 

• Proactively identify, document, and resolve risks through the Risk Management program. 

• Compliantly drive issues to resolution 

• Apply expertise of CGT Supply Chain and enable development of that expertise within the team and cross-functionally 

• Interacts with senior level management 

• Create content for executive level presentations on critical supply chain issues, initiatives, and projects. 

• Participate in creating functional/department goals  

• Drive system requirements, compliance, testing, and utilization to meet the needs of patients. 

• Support the development of potential agentic AI solutions for slot management by contributing to solution design, cross-functional discussions, and practical recommendations that help shape scalable and effective approaches. 

• Identify and implement new processes and capabilities needed to support Cell and Gene Therapy programs. 

• Anticipate future industry trends and keep abreast with a strong foundation of knowledge of manufacturing, development, and supply 

Minimal Requirements:  

• Bachelor's degree in a scientific or business discipline preferred, or equivalent years of relevant experience 

• 6+ years of Biotech, Pharmaceutical or medical device company related work experience 

• Ability to analyze straightforward problems and develop possible solutions using technical experience and judgment; may escalate unusual or complex problems   

• Ability to effectively balance customer expectations with internal/team expectations  

• Exhibits robust knowledge across supply chain disciplines 

• Demonstrates strong aptitude for managing and motivating others and building team unity 

• Proven ability to manage multiple projects with high degree of effectiveness 

• High level understanding of GMP processes and regulatory requirements 

Strong written and verbal communication skills to exchange relevant, and at times complex, information cross-functionally and ensuring understanding