Director, Global Commercial Strategy (GCS) Oncology – Portfolio Strategy

Use Your Power for Purpose

Oncology is an exciting and dynamic area and a key priority for Pfizer. This role has the potential to help set the future vision for Pfizer’s Oncology portfolio and to help make a significant difference in patients’ lives. The Director, Global Commercial Strategy – Oncology is responsible for working with research, development, marketing and the cross-functional team to drive commercial decision-making for the early-stage, late-stage and business development opportunities in the Oncology pipeline. This role will be responsible for long term vision, commercial assessment, and investment case development for a range of early / late-stage assets, life cycle options and technology platforms. In addition, the role will also be responsible for leading / supporting key strategic initiatives portfolio-wide.

What You Will Achieve

The candidate must be a self-starter who is able to multitask in a fast-paced and dynamic environment and support the team through key strategic decisions for Pfizer’s oncology portfolio.

Key responsibilities include:

This position will be a key interface to Global Marketing, R&D, Medical, Regulatory, PDA, GAV, BD, and all partner functions to facilitate execution of asset plans and support asset progression through governance stage-gates and endorsements by OSGT and enterprise governance bodies. He / She will play an important influential leadership role to foster a strong, collaborative partnership culture.

Lead commercial / strategic assessments and drive commercial planning to support development of asset / technology platform business cases, including:

1) Evaluating and maintaining a comprehensive view of the dynamic competitive landscape at the asset / MOA / tumor / oncology level

2) Leading comprehensive analysis of market trends, treatment trends, evolving standard of care and competitive developments globally

3) Providing commercial input to the development strategies to optimally develop assets

4) In close partnership with key stakeholders, drive pipeline asset and disease area strategies, commercial assessments, product concepts, target product profiles, strategic scenario planning, and asset investment decisions.

Make appropriate strategic and investment recommendations to OSGT, PMT and Pfizer governance bodies.

Create and update portfolio decision making tools and systems to provide state-of-the-art tools that are aligned and applied consistently across the portfolio.

Here Is What You Need (Minimum Requirements)

· Applicant must have a bachelor's degree with at least 8 years of experience; OR a master's degree with at least 7 years of experience; OR a PhD with 5+ years of experience

· Experience in commercial development, marketing, new product launch or strategy in pharmaceutical, medical device or biotechnology companies

· Experience in Strategy Consulting and/or Commercial organizations is preferred

Bonus Points If You Have (Preferred Requirements)

· Strong understanding of Oncology landscape and emerging trends

· Prior Commercial Development experience with commercial planning, decision-making and driving value of early-stage pipeline assets

· Experience progressing assets through stage-gates (POC, DP3 etc) and presenting asset business cases to senior management

· Hands-on experience leading financial valuation, forecasting, business proposal and/or other related projects

· Experience interfacing/collaborating with Research, Development, Regulatory, and other functions

· Ability to influence without direct authority

· Demonstrated leadership of cross functional matrix teams and developing a collaborative culture

· A high sense of urgency with a focus on driving decisions in the face of incomplete and imperfect information

· Experience in long term strategic plan development and execution

· Experience with global product launches and developing pre-launch positioning and strategies

· Advanced degree 
· Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

Last Day to Apply: July 10, 2026

Work Location Assignment: Hybrid


The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.



This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.




Relocation assistance may be available based on business needs and/or eligibility.




Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.






To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.


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