About the Job

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions. 

Sanofi is a leading bio-pharmaceutical company committed to advancing healthcare through groundbreaking research and development. Our dedicated function – Clinical Sciences & Operations (CSO) - plays a vital role in ensuring accurate and compliant clinical trial submissions and project operations, contributing to the approval of innovative therapies that transform patients' lives.

Within CSO, the Modernization & Performance Office (MPO) acts as a key enabler of transformation and modernization, driving strategic initiatives that enhance efficiency, digital innovation, and operational excellence across the function. As we continue our business transformation and drive excellence and innovation in our processes, we are seeking an exceptional professional to join us as Digital Acceleration & Innovation Lead.

The Clinical Digital & AI Acceleration innovation Manager is a CSO-wide, function-level leadership role reporting to the Head of Clinical Digital & AI Acceleration, with explicit accountability for shaping, steering, and realizing the value of CSO’s digital and AI transformation agenda across Sanofi’s Clinical Sciences & Operations (CSO).

The role operates as a strategic authority rather than a delivery contributor, responsible for orchestrating global-scale digital and AI transformation across clinical development, with decision rights on portfolio prioritization, investment trade-offs, resource allocation, and execution strategies within the transformation portfolio. The incumbent directly influences CSO operating model evolution, ensuring that digital and AI initiatives fundamentally reshape how clinical trials are designed, executed, and governed globally, with measurable business, quality, and patient impact.

The position combines strong digital and AI domains with function-level business and transformation leadership, requiring the ability to produce decision-grade insights for CSO leadership, translate complex technology and regulatory constraints into strategic value hypotheses, and steer outcomes across highly matrixed, regulated environments. The role also leverages competitive and technology intelligence to proactively shape CSO strategic choices.

If you are a visionary leader with a passion for transforming clinical operations processes and driving innovation in clinical research, we encourage you to apply for this exciting opportunity. Join our team and contribute to our mission of improving patient outcomes through cutting-edge therapies.

Main Responsibilities

 

Portfolio Management

• Co-own and lead CSO Digital & AI transformation initiatives at function level, ensuring alignment with CSO strategy, business priorities, and value realization commitments.

• Exercise decision authority on initiatives prioritization, sequencing, and trade-offs to maximize CSO-wide value and time-to-impact.

• Align strategically and operationally CSO’s flagship transformation initiatives (e.g., ACT4Patients & eDEV) to ensure coherence, integration, and early realization of business outcomes

• Continuously challenge and recalibrate the transformation roadmap based on business performance data, field feedback, and competitive intelligence

• Ensure global visibility and governance alignment across all internal and external digital innovation initiatives (Clinical Innovation, external forums, partnerships, etc.)

• Evolve the Initiative Portfolio Management Office (iPMO) as a CSO governance and decision-enablement mechanism, not a procedural framework

• Define, institutionalize, and enforce governance standards (business cases, ROI logic, value tracking, scale-up criteria, stop/pivot decisions)

• Hold transformation teams accountable for outcome-based delivery and value realization, beyond milestone completion

 

Transformation Projects Leadership and Engagement management

• Lead and sponsor selected high-impact, multi-million-euro, clinical-development critical transformation programs with Digital and/or AI components

• Accountable for end-to-end outcomes, including strategic alignment, financial performance, adoption, scale-up, and sustained value delivery

• Direct and validate: Competitive and technology intelligence to inform strategic positioning, function-level business needs and value hypotheses, prioritization of business-driven requirements shaping product and roadmap decisions & gaps analysis against existing solutions and operating models

• Provide strategic direction on vendor models, sourcing strategies, and contractual frameworks in alignment with CSO transformation priorities

• Oversee financial planning, investment phasing, and resource allocation to optimize enterprise ROI

• Influence CSO-wide positioning and integration of strategic platforms (e.g., NEXUS, TrialPulse, Concierge)

• Ensure successful enterprise deployment and scale-up, tracking realized benefits beyond pilot or proof-of-concept stages

• Own risk, dependency, and performance steering, escalating and arbitrating at CSO leadership level as required

Digital & AI Acceleration Capability Building

• Define and own CSO-wide frameworks for measuring ROI, business impact, adoption, and maturity of digital, data, and AI initiatives

• Provide portfolio-level, decision-grade visibility on solution interdependencies, capability impacts, and end-to-end process transformation

• Institutionalize lessons learned and drive continuous improvement across the CSO transformation ecosystem

• Continuously scan and interpret external technology, AI, and regulatory trends, translating them into actionable CSO transformation opportunities

Stakeholder Engagement & Collaboration

• Engage, influence, and challenge CSO senior leadership and executive stakeholders as a trusted transformation and governance partner

• Represent portfolio status, risks, and value realization in executive governance forums, providing clear recommendations and decision options

• Co-lead CSO-level digital and AI strategy forums, shaping leadership understanding and adoption of innovation

• Build and maintain enterprise partnerships beyond CSO (TMU, GRA, PV, Digital, etc.) to accelerate transformation at scale

• Act as an enterprise integrator between business, technology, and data teams, ensuring alignment and accountability

 

About You

Experience:

• Minimum 8 years of experience in enterprise digital transformation, portfolio leadership, or strategic program governance

• Proven track record leading large-scale digital, data, or AI-enabled transformation in complex, regulated environments

• Strong experience in BVA modeling, ROI tracking, and benefit realization

• Proven ability to influence executive decisions and steer outcomes without direct hierarchical authority

• Understanding of clinical development, with enterprise exposure to GCP, ICH-GCP, and operational quality frameworks

 

Leadership and Behavioral Competencies:

• Function-level strategic and systems thinker, able to connect initiatives to value chains and operating-model shifts

• Strong analytical rigor combined with executive judgment and decisiveness

• Credible, confident presence at senior leadership and executive level

• Outcome- and value-oriented mindset with clear ownership and accountability

• Excellent cross-functional, cross-cultural leadership and orchestration skills

Education:

• Master's degree or PhD in a relevant field such as (but not limited to): Computer Science, Data Science/Analytics, Engineering (with focus on AI/ML). MBA will be a plus.

Languages

• Fluent in English

Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:

$178,500.00 - $257,833.33

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.