Sr Principal Eng - Process Engineering

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world.  We provide an inclusive work environment where each person is considered as an individual.  At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Supply Chain Engineering

Job Sub Function:

Process Engineering

Job Category:

Scientific/Technology

All Job Posting Locations:

Gurabo, Puerto Rico, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way!

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Sr Principal Eng - Process Engineering to join our Team! This is an onsite/hybrid role.

Please note that this role is available across multiple countries and may be posted under different requisition numbers to align with local requirements. While you are welcome to apply to any or all of the postings, we recommend focusing on the specific country(s) that align with your preferred location(s):

Belgium & Italy- Requisition Number: R-071736

Puerto Rico - Requisition Number: R-076777

Switzerland - Requisition Number: R-076783

Remember, whether you apply to one or all of these requisition numbers, your applications will be considered as a single submission.

Position Summary

As the GET PE – Synthetics Drug Product Manufacturing Senior Principal Engineer, you will lead early design inputs and technical strategy for synthetic’s drug product manufacturing processes within strategic capital projects, network studies, and technology platforms across IMSC. You will provide deep technical expertise in the synthetic’s controlled bioburden-drug product manufacturing (OSD and innovative forms such as semi-solid) and drug product intermediate through bioavailability enhanced technologies, while supporting solving and optimization activities at internal and external manufacturing sites.

Joining our global engineering group, you will collaborate with high‑performing, multi-functional teams across multiple sites and functions. This role offers a dynamic and inspiring work environment with significant opportunities to influence technology direction, standardization, and capability building across the network.

Responsibilities and impact you will have:

• Lead the intake, scoping, prioritization, and resolution of synthetics controlled bioburden- drug product manufacturing related technical requests across global sites

• Lead and influence early‑phase process design and domain expertise for oral solid dose (OSD) products, covering both batch and continuous manufacturing platforms; as well new innovative drug product forms

• Lead and influence early‑phase process design and domain expertise for bioavailability enhanced technologies, including amorphous solid dispersions (ASD) with a strong emphasis on spray drying, as well as other technologies such as Self-Emulsifying Drug Delivery Systems (SEDDS) and other related innovative drug product intermediate formulation approaches

• Ensure robust, fit‑for‑purpose process design while promoting standardization and platform approaches where they make valuable contributions

• Provide expert input and alignment on key process, equipment, and technology selection decisions for drug product manufacturing

• Actively collaborate with other functions such as R&D, MSAT, Quality, EHS and Operations leads across synthetic drug product sites

• Find opportunities for harmonization, shared solutions, and best‑practice exchange across the network

• Foster a culture of collaboration to reduce duplication, accelerate implementation, and improve speed‑to‑market

• Maintain strong connections with industry experts and external networks (e.g., ISPE) to bring innovative drug product manufacturing solutions into the organization

• Ensure alignment with enterprise strategies, GMP requirements, and technology roadmaps

• Collaborate with External Manufacturing teams to prioritize support and resolve issues for high‑impact programs and partners

Qualifications

Required:

Education:

• Minimum of a Master’s degree or equivalent experience in Engineering, Pharmaceutical Sciences, or a related technical field is required

Experience and Skills:

• Minimum 10 years of relevant experience in synthetics controlled bioburden drug product manufacturing, with a strong focus on oral solid dose (OSD) processes and innovative technologies (e.g semi-solid) in drug product pharmaceutical manufacturing environments

• Demonstrated expertise in bioavailability enhanced technologies, including ASD (amorphous solid dispersions)—with deep knowledge of spray drying—and SEDDS or similar innovative enabling formulation approaches

• Proven experience with OSD controlled bioburden manufacturing, including batch and continuous manufacturing processes and associated equipment

• Strong understanding of cGMP environments and regulatory expectations for controlled bioburden-drug product manufacturing. Aseptic capability is a plus

• Proven track record of leading multi-functional teams and influencing technical decisions in complex, global organizations

• Ability to support early‑phase design, detail design, Start‑up processes and Commissioning & Qualification (C&Q) of controlled bioburden (and aseptic) equipment

• Experience with inherently safe containment design for components with low exposure level

• Drive the adoption of digital and data‑enabled solutions for DP manufacturing, including real‑time monitoring, advanced process control, advanced analytics, model and simulation, and smart manufacturing use cases where they improve reliability and performance

• Strong customer management and communication skills, with the ability to influence across sites, functions, and external partners

• Strategic attitude combined with hands‑on technical capability

• Intellectual curiosity to challenge the status quo, influence without authority, and cultivate an inclusive and collaborative culture

• Proficiency in written and spoken English

• Willingness to travel up to 25% domestically and internationally

Preferred:

• Strategic attitude combined with hands‑on technical capability

• Intellectual curiosity to challenge the status quo, influence without authority, and cultivate an inclusive and collaborative culture

• Additional languages (Dutch, Spanish, Italian) are an advantage

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please contact us via https://www.jnj.com/contact-us/careers or contact AskGS to be directed to your accommodation resource.

Required Skills:

 

 

Preferred Skills:

Agile Decision Making, Coaching, Consulting, Corrective and Preventive Action (CAPA), Crisis Management, Cross-Functional Collaboration, Disruptive Innovations, Emerging Technologies, Industrial Hygiene, Lean Supply Chain Management, Process Control, Process Engineering, Product Costing, Program Management, Project Schedule, Science, Technology, Engineering, and Math (STEM) Application, Tactical Planning, Technical Credibility, Technical Research

 

 

The anticipated base pay range for this position is :

$116,000.00 - $200,100.00

Additional Description for Pay Transparency:

Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).
Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits:
• Vacation –120 hours per calendar year
• Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
• Holiday pay, including Floating Holidays –13 days per calendar year
• Work, Personal and Family Time - up to 40 hours per calendar year
• Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
• Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
• Caregiver Leave – 80 hours in a 52-week rolling period10 days
• Volunteer Leave – 32 hours per calendar year
• Military Spouse Time-Off – 80 hours per calendar year
Additional information can be found through the link below.
For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits