Location
Boston, MA
Compensation
$147k–$221k USD
Market range · company + function + seniority
p25 · target · p75 · n=12
Posted $221k · in the market band
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Job Description
General Summary:
The Principal Scientist, Stem Cell Research provides scientific leadership and ownership of stem cell differentiation, characterization, and assay strategies supporting Vertex stem cell therapy programs. This is a hands‑on, lab‑based role with responsibility for defining experimental direction, setting scientific standards, and driving decision‑making for complex stem cell-derived cellular platforms.
The Principal Scientist serves as a subject‑matter expert and scientific authority, guiding strategy, assessing risk, and integrating biological, technical, and data‑driven evidence to advance robust differentiation and characterization approaches toward preclinical and IND‑enabling objectives. This role directly influences program strategy and milestones through independent scientific judgment and cross‑functional collaboration.
Key Duties and Responsibilities:
Knowledge and Skills:
Education and Experience:
Pay Range:
$147,200 - $220,800Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
On-Site DesignatedFlex Eligibility Status:
In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Onsite
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
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