Principal Enterprise Architect - AI & Agents

Job Summary

Job Overview

·                     Published and broadly adopted AI and agent reference architectures

• Increased reuse of shared services, patterns, and templates
• Reduced duplication of AI implementations and development efforts
• Faster architecture reviews and approvals with fewer exceptions
• Improved compliance readiness for regulated and high‑risk AI workloads

Key Responsibilities

·                     Define, maintain, and evolve enterprise reference architectures, standards, and reusable patterns for generative AI and agentic systems.

• Govern solution designs, including selection of appropriate technical components, ensuring delivery teams can adopt standards with minimal friction.
• Provide architectural oversight for major AI initiatives, guiding trade‑offs across security, compliance, scalability, cost, and time‑to‑value.
• Translate business strategies and OKRs into capability‑based roadmaps and target‑state architectures, avoiding project‑specific point solutions.
• Drive enterprise interoperability across systems and data domains by defining integration patterns and data exchange approaches aligned with enterprise standards.
• Partner with compliance, risk, and information security teams to ensure architectures align with global regulatory and quality expectations (e.g., GxP, GDPR, HIPAA, EU AI Act).
• Maintain enterprise capability models and architecture artifacts using EA tools (e.g., LeanIX, Ardoq, MEGA), mapping capabilities to processes, systems, products, outcomes, and key data domains.
• Identify opportunities to consolidate platforms and services across business units, quantifying investment implications and business benefits.
• Guide senior stakeholders through architectural options, trade‑offs, and investment decisions using clear, business‑focused narratives and models.
• Monitor AI, agentic, and life sciences technology trends; assess relevance and fit; and inform enterprise roadmaps, reference architectures, and innovation priorities.
• Mentor and influence architects and senior engineers to raise overall architecture maturity and adherence to enterprise standards.

Required Qualifications

·                     10+ years of experience in enterprise or application architecture within large, complex organizations, including ownership of standards, roadmaps, and governance.

• Proven experience designing and scaling generative AI and agentic solutions, with a strong focus on reusable patterns and operationalization.
• Deep technical knowledge of generative AI and agentic concepts, including vector databases, RAG, tool‑use, MCP servers, HITL, evaluation frameworks, monitoring, observability, and platforms such as LangGraph.
• Strong cloud architecture experience on Azure and/or AWS, including modern data architectures (lakehouse, governance, cataloguing).
• Expertise in modern integration styles (API‑first, event‑driven, microservices) and the ability to codify them into enterprise standards and reference architectures.
• Exceptional communication, influence, and stakeholder management skills, including engagement with senior business, product, and technology leaders.
• Experience building business cases for modernization, rationalization, and platform consolidation initiatives.

Preferred Qualifications

·                     Experience in healthcare or life sciences, with strong knowledge of the clinical trial lifecycle, real‑world evidence, or commercialization of clinical assets.

• Hands‑on partnership with CRO business teams, including study design, site activation and management, clinical operations, regulatory affairs, medical affairs and KOL engagement, real‑world safety and efficacy, pharmacovigilance, and EMR ecosystems.
• Proficiency with enterprise architecture tools (LeanIX, Ardoq, MEGA, or similar) and formal capability modeling methodologies.

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com

IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe

IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.

The potential base pay range for this role, when annualized, is $118,100.00 - $328,800.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.