Global Commercial Lead, Rare Neurology

At Alexion, AstraZeneca Rare Disease, we are innovators, leaders, and collaborators. At the heart of everything we do is an intense desire to pursue the toughest challenges and truly change the world for people living with rare and devastating diseases.

Alexion’s Global Marketing and Market Access team (GMMA) is an integrated commercial strategy and operations team, whose core objectives are to develop disease and brand commercial strategies and translate those strategies into highly impactful global tactics. To maximize their impact, GMMA seeks local perspectives in strategy and tactic development and strives to deliver outputs that drive successful local launches and sustained performance.

Post-launch, the GMMA team diligently monitors the performance of the business and the effectiveness of our strategies, helping to position our brands for broader access and sustained long-term success.

In the Rare Neurology Disease Areas, Alexion has a bold strategy, backed by an impressive pipeline, giving team members opportunities to drive progress and outcomes across pipeline, launch, and inline phases.

Our unique culture thrives on collaboration, authenticity, creativity, and pushing boundaries in all that we do to advance patient care.

THE ROLE:

The Senior Global Commercial Lead, Rare Neurology is an important role that will work with local Rare Disease teams and cross-functional partners to drive commercial development of ALXN-2230. This role will build upon their market expertise and best practice insights to drive the planning for and deliver successful launch of ALXN-2230 in IIM, wAIHA, and gMG

This role provides leadership within a matrix working model between global and local markets and across functions.  Working in complex and competitive markets, the role is accountable for creating a collaborative and high-performance environment that supports the innovation required to identify and realize substantial value opportunities.

You will be responsible for:

• Commercial Development of ALXN2230:
  • Liaise with medical, clinical, and broader cross functional partners to ensure optimal clinical trial design, thus ensuring maximal commercial opportunity
• Launch:
  • Ensure organization launch readiness at the local level
  • Collaborate with cross-functional partners, particularly Global Market Access, Global Medical, Insights & Analytics, Operations, and Regulatory.
  • Support the onboarding of markets (in waves) to the ALXN2230 program and relevant disease areas.
  • Devise and disseminate critical information required for markets to:
    • Prepare and submit business cases within tolerance on time, cost, and quality, working with functional management as required to resolve issues.
    • Develop their bottom-up, three-year performance and investment assumptions for MTP
    • Ensure organization launch readiness at the local level
    • Align with the global launch strategy, sequence, and supply
  • Support the design and delivery of Launch Readiness Reviews (LRRs), Deep Dives, and TA Connects:
    • Work with Global Launch to customize the G2M LRR framework for ALXN2230
    • Determine optimal LRR sequencing/grouping of countries for global to review launch plans, assess launch readiness, and encourage cross-sharing of innovative ideas
    • Work with Global, Regional, and Local planning teams to organize any in-person LRRs and/or plan for optimal virtual or hybrid sessions
    • Run deep dives, LRRs, and TA connect meetings with key countries, with the Global Disease and/or Brand Strategy Leads and cross functional team.
  • Contribute to the GOLT governance structure and NPI process to ensure Commercial input to required decisions and planning is completed on time.
  • Responsible for supporting your value and access counterpart to evaluate and advise countries on their access business cases.
  • Support countries elevate functional needs to the Region and Global, e.g., pricing, market access or regulatory strategy, market shaping, local studies or evidence generation.
  • Responsible for providing country input into global commercialization plans to ensure that commercialization priorities are appropriately considered, visible and supported.
• Global Commercialization Strategy Execution: implement global commercialization disease strategies, launch plans and tactical plans. Assist core markets in adapting and executing these strategies, ensuring best practices are shared and global strategy is synchronized across functions to optimize business performance.
• Capabilities:
  • You constantly strive to be the best at what you do. This includes regularly scanning the external landscape for innovative ideas, tactics, technologies, vendors/partners, etc. 
  • You identify and support the building of local market capabilities that drive innovative commercialization, including go-to-market strategies and above-brand goals
• Strategic Projects:
  • You are a strategic and experienced business leader who actively contributes to key initiatives and above-brand projects within your space and the broader organization.

You will need to have:

• Bachelor’s degree in Business, Medical or Life sciences degree
• 10 years pharmaceutical commercial experience
• Expertise in neurology, hematology, and/or rare diseases
• Commercial experience including pre-launch and launch
• Proven experience and knowledge of a broad base of external customers including patients, prescribers, payers and providers
• Experience using clinical data to shape brand strategies and lifecycle planning
• Experience with revenue forecasting, budget/expense management, business case development and management/communication of brand performance.
• Strong understanding of technical risks and the implications for the commercial aspects to future brands
• An in-depth technical knowledge in all commercialization aspects (commercial, market access and medical) and most preferably proven understanding of the disease areas of interest
• Strong leadership experience and the ability to coordinate and drive complex projects

We would prefer for you to have:

• An advanced degree (MBA, MSc or PhD) is preferred

The annual base pay for this position ranges from $231,988.80 - $347,983.20 USD Annual . Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. 

Date Posted

20-May-2026

Closing Date

14-Jun-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.