Senior Production Operator (SPO) III, Night Shift

Use Your Power for Purpose

Our breakthroughs would not make it to the hands of patients without our pharmaceutical manufacturing team. We rely on a team of dedicated and agile members who understand the importance and impact of their role in Pfizer’s mission. Patients need colleagues like you who take pride in their work and always look to improve outcomes. You will help to ensure that patients and physicians have the medicines they need when they need them.

What You Will Achieve

In this role you will:

• Self-motivated with ability to work in a team environment and independently.

• Work in a clean manufacturing environment, requiring special garments to be worn. Demonstrated proficiency in gown/de-gown (i.e. aseptic) process. Responsible for the proper operation of production equipment, equipment downtime, and scrap rate.

• Perform machine set-up, repairs, adjustments, changeovers, emergency repair/replacement, and preventative maintenance on production equipment per the applicable procedures.

• Interact and interpret data from production equipment automated control systems and displays.

• Adhere to all safety requirements (e.g. PPE, LOTO, etc.) and process step requirements (e.g. SOP, Batch Records).

• Communicate and inform management of all safety issues, quality issue, and equipment repair plan of action recommendations.

• Communicate effectively with team members and management to achieve production deliverables and schedule adherence.

• Support the Integrated Manufacturing Excellence (IMEx) activities (e.g. Continuous Improvement (CI), Standard Work (SW), and Total Productive Maintenance (TPM) including tracking metrics).

• Demonstrated proficiency in current Good Manufacturing Practices (cGMP), Good Documentation Practice, and following detailed instructions.

• Demonstrated proficiency working work with automated production equipment.

• Demonstrated proficiency in troubleshooting and Root Cause analysis.

• Certified Trainer. Coaches and trains new hires.

• SME of the production equipment within respective area.

• SME for operations and technical resources outside the department.

• Partners with PES in planning and organizing shutdown activities.

Here Is What You Need (Minimum Requirements)

• 3-6 years of pharmaceutical manufacturing experience.

• Requires High School Diploma (or Equivalent).

• Problem solving mindset.

• Possess necessary mechanical skills to perform the required machine set-up, repairs and adjustments in order to keep equipment operating efficiently.

• Proficiently operate/maintain various standard maintenance tools/equipment including basic hand and power tools, multi-meters, and other mechanical equipment.

• Ability to read, interpret, and perform job duties described in operating procedure, product batch records, and other equipment related documentation (e.g. vendor manuals, P&ID, schematics, drawings, etc.).

Bonus Points If You Have (Preferred Requirements):

• 5+ years of relevant pharmaceutical manufacturing experience as operator/mechanic.

• Technical school/ Auto Mechanic Program Certificate and/or Industrial maintenance/repair experience.

Physical/Mental Requirements

• Stand 8-12 hours per shift, sit 2-4 hours per shift, use computer terminal 1 hour per shift.

• Change into area required garments (i.e. scrubs, shoes, PPE, safety glasses) 2-3 times per shift.

• Work around moving/rotating equipment, work around chemicals, work in hearing conservation area, work on knees or non-standing position occasionally for repairs. Requires physical activity for equipment repair, adjustment and operation of equipment.

• Respond to visual/audible warning and alarm indicators, respond to color or other visual indicators.

• Walk on floors/catwalks, climb stairs/ladders.

• Must be able to lift up to 50 pounds.

Non-Standard Work Schedule, Travel, or Environment Requirements

• Support production schedule and project schedule which may require after hour support and weekend coverage.

• Ability to work overtime as required.

• Travel required only for special projects if assigned.

Other Job Details

• Last day to apply: May 15th, 2026.


The salary for this position ranges from $25.88 to $43.14 per hour. In addition, this position offers eligibility for overtime, weekend, holiday and other pay premiums depending on the work schedule and the Company’s policies. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided applies only to the United States - Kansas - Mcpherson location.





Relocation assistance may be available based on business needs and/or eligibility.




Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.






To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.


Manufacturing